Pharmaceutical sector

We develop new machine designs and technically update existing machines and equipment to comply with international standards and norms (GAMP5, CFR.21, FDA, ISO.S.95).

 

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Pellet lines

Pellet production lines can be designed for manual or automatic operation. The main components consist of a dosing unit to feed an extruder that produces "vermicelli", which are formed into pellets inside the Spheronizer and then cooled. The pellet production lines can be extended and adapted in numerous ways to automate and optimise the operation.

Components of the line
Main components: Dosing unit, extruder, Spheronizer cooling unit
Extensions: Lifting column, feed hopper, batch portioner, grinder

Capacity & options
5 - 80 kg/h, pellet line manual
5 - 100 kg/h, pellet line automatic
Ex-protection

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Extruder

Extruders with independent heating zones according to user requirements provide the required accuracy for each pharmaceutical product. The co-rotating extruder screws can be configured to meet all process requirements. Our extruders range from laboratory models to complete production machines that allow production "upscaling".

Depending on the process, the machines can be integrated into a complete line or act as a stand-alone machine.

Gabler Spheronizer

Spheronizer

Spheronisers are available from laboratory models to automatic production lines with GMP design for the pharmaceutical industry. Various options, such as explosion protection, offer the flexibility to master any pellet forming process

Production data:

  • Pellet dimensions from 0.4 to 5mm
  • Batch size from 0.15 to 6 kg
  • Rounding time from 1 to 5 minutes
Gabler dosing unit

Dosing machines

Dosing machines - volumetric- dry or wet powder

The Dosimex volumetric dosing unit is typically used to provide DE-type extruders with a constant supply of dry or moist powder. The Dosimex offers a wide range of possibilities as it can be used as a stand-alone machine, or integrated into the extruder's control system, depending on the application. The GMP design for the pharmaceutical industry makes this machine easy to clean, as the parts in contact with the product can be dismantled without tools.

Capacity:

  • Output from 10-300 kg/h with dry powder
  • Output from 5-200 kg/h with moist powder
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Feed hopper

Batch proportioners are part of many pellet production lines as they collect the extruded vermicelli in a hopper, when the required weight is reached they are automatically transported to the spheroniser. The GMP design meets the hygiene requirements of the pharmaceutical industry.

Options

  • Explosion protection
  • Heatable funnel
  • Separate control
Gabler coating machine

Coating machines

Coating machines - fixed or swivelling - Laboratory coating machines

Gabler supplies fully automatic coating systems with a boiler in onion or pear shape, depending on the application. Our innovative spray technology and extensive drying system ensure the shortest coating times in this sector. Recipe management and individual adjustment or regulation of the coating angle offer various possibilities to improve existing coating processes or test new ones before scaling them up to a production line.

Capacity

  • from 20 kg to 1000 kg per batch¬†

Application

  • Film bearing
  • Suspenion dragging